ANALGESICS Non-opioid analgesics  

AMH 2022 section 3.1.1

Active ingredients (generic names)

PARACETAMOL (para-ceet-a-mol)

Capsules and tablets

Mixture.

Medicine dropper.

medicine - slow-release

Suppositories.

Paracetamol combinations

Not included in this monograph — see individual monograph for information:

Paracetamol is in lots of commonly available mixtures and tablets, alone or in combination.

What it is used for

Doses

How it works
  • Reduces pain by blocking some pain pathways
  • Lowers fever by reducing production of prostaglandins (hormone-like substances)
  • Can be combined with stronger pain medicines (analgesics) — so less of the stronger pain medicine is needed

Brain and spinal cord.

Side effects

Nausea and vomiting

Diarrhoea

Warnings
  • Do not give tablets closer together than 4 hours for regular tablets or 6 hours for slow release tablets (can cause liver damage)

liver - trouble.jpg

Liver trouble

Medical consult

If needed for more than a few days for adults or 48 hours for children 

Emergency

if a lot of tablets taken at once (overdose) — call doctor or ambulance straight away
Tell the patient
  • Make sure children are given correct dose
    • Children's paracetamol comes in different strengths
    • Use specially marked medicine cup or dropper
  • Taking more than 6 slow-release or 8 regular tablets containing paracetamol in one day can damage your liver
    • If taking paracetamol for pain or fever — make sure there is no paracetamol in other medicines you are taking (eg cold medicines, osteoarthritis medicines)

Return to clinic

if needed for more than a few days for adults or 48 hours for children OR you take too much

Warning stickers: 19axref-slash iconAxref-slash icon (slow-release tablets)

Check
  • Children's paracetamol comes in different strengths — check the dose carefully
  • Do person's other medicines contain paracetamol OR dosing aid contains paracetamol
  • If also taking warfarin — monitor INR and decrease warfarin dose if needed