ANTI-INFECTIVES Antibacterials Macrolides

AMH 2022 section 5.1.6

Active ingredients (generic names)

AZITHROMYCIN (a-zith-row-my-sin)

ROXITHROMYCIN (rox-ith-row-my-sin)

Tablets

Mixture.

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Other macrolides

Not included in this monograph — see AMH for information:

  • Clarithromycin
  • Erythromycin
What it is used for
  • Used to treat infections, eg STIs, sore throat and trachoma

Doses: Azithromycin

How it works
  • Antibiotic that stops bacteria cell from making proteins, so it can't grow
  • Different germs need different antibiotics. If not sure which one to use — check with doctor
Side effects

Nausea and vomiting

Diarrhoea

Abdominal pain

Headache

Warnings
  • Ask about allergies

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Babies under 6 months
(limited information)

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Liver trouble

Interactions — Do not use together without medical consult

AZITHROMYCIN with

  • Digoxin
  • Theophylline
  • Warfarin

ROXITHROMYCIN with

  • Digoxin
  • Warfarin
Tell the patient
  • Take all the medicine — makes sure all the germs are gone and the infection doesn't come back

Take on empty stomach
(roxithromycin)

Finish medicine
— even if you feel better

Warning stickers: Azithromycin medicine mixture 7axref-slash icon Roxithromycin 3bxref-slash icon

Check

Making mixture (azithromycin)

Make sure right amount of clean water added to dry powder

  • Follow-up when antibiotic treatment finished to make sure infection is gone. If not — medical consult